At the 2021 United Nations Climate Change Conference (COP 26) in Glasgow, the U.S. recommitted to necessary and ambitious climate goals. Political trade winds may threaten climate-smart policies, but in this season of reflection, renewal, and resolutions, we find reasons for hope. Health leaders can continue seizing the greatest opportunity of the century by working to: build workforce capacity, build community resilience, and reverse the drivers of climate change.  We also must continue fighting for strong climate policies that improve our health.